smokingFull doseFullEarly signal

Twelve of fifteen smokers quit and stayed quit

An 80 percent abstinence rate that nobody has matched since.

2014Published
Open-label pilot studyStudy type
15 peopleSample
What our evidence ratings mean

What they did

Fifteen long-term smokers at Johns Hopkins, averaging thirty-one years of smoking and six previous quit attempts, received moderate and high doses of psilocybin inside a fifteen week cognitive behavioural quit programme.

What they found

Biologically confirmed abstinence at six months was reached by twelve of fifteen participants, or 80 percent, against the rates below 35 percent typically seen with standard treatments.

12 of 15abstinent at 6 months
31 yrsaverage smoking history

Worth knowing

Fifteen people, open-label, no control group, and a highly motivated self-selected sample wrapped in an intensive therapy programme. The 80 percent figure travels far further than the evidence behind it.

Johnson et al. Pilot study of the 5-HT2AR agonist psilocybin in the treatment of tobacco addiction. Journal of Psychopharmacology, 2014.

Read the source

A lot of our customers arrive from the sober curious side rather than the psychedelic side. If that is you, the alcohol research below is the most relevant on the whole shelf. See what we make.

For education, not medical advice. Every write-up links back to the original source.
Nothing here is a claim that our products treat, cure or prevent any condition. Talk to a doctor before changing anything about your health.