Macrodosing 101

A full experience.

A macrodose is a full psychedelic experience: deeper, longer, and considerably more involved than a microdose. The intent is different. The preparation is different. The dose is different.

What is macrodosing?

300mg and up.

Macrodosing means taking a full perceptual dose of psilocybin, typically between 300mg and 5g of dried mushroom, for a directed experience. Effects begin 30 to 60 minutes after taking it and last 4 to 6 hours.

Unlike a microdose, this is something you set time aside for. People macrodose for spiritual or introspective reasons, for emotional release, or for social and creative experiences with intent.

Important.

This is not a recreational casual dose. Plan ahead. Don't drive. Don't macrodose alone for your first time. Read our preparation guide first.

Dose guide

By intention.

Mild · 300-700mg

Slight perceptual shift. Mood lift, body warmth, gentle pattern noticing. Suitable for first-timers or social settings with trusted people.

Full · 1-2.5g

A proper psychedelic experience. Visual changes, emotional depth, dilated time. Plan a clear 6-hour window. Sitter recommended for first time.

Deep · 2.5g+

An immersive experience. For experienced macrodosers with intention. We strongly recommend a sober sitter and a prepared setting.

Preparation matters

Set and setting.

The two strongest predictors of a good experience are mindset and environment.

Set: your headspace. Are you stressed, anxious, recently bereaved, in conflict? If yes, postpone. Macrodoses amplify whatever is already in the room.

Setting: your space. Quiet, familiar, comfortable. Phones off. Hydration nearby. A sitter you trust, especially the first time. Nature works. Bedroom works. Crowded bars do not.

Day-of checklist

Eat lightly 2 hours before
Hydrate well
Phone on do-not-disturb
Music ready, headphones nearby
Blanket, journal, snacks
Nothing on the calendar for 8 hours
Sober support available

During the experience

What to expect.

First hour

Body warmth, slight visual softening, mood lift. Some nausea is normal. It passes.

Peak · 2-3hr

Strongest visuals and emotional content. Time feels different. Lean in, breathe.

Coming down

The intensity softens. Insights start crystallising. Good time for music or quiet.

Safety

Honest safety notes.

Who shouldn't macrodose?+

Anyone with a personal or family history of psychosis, schizophrenia, or bipolar disorder. Anyone on lithium. People with serious heart conditions. Pregnant or breastfeeding people. When in doubt, ask your doctor.

What about bad trips?+

Hard moments happen. They're usually the most valuable part. A trusted sitter, a quiet space, slow breathing, and changing your music or setting almost always shifts the experience. Don't fight it. Let it move through.

How do I integrate after?+

Journal that night and the next morning. Move your body the next day. Talk it through with someone you trust. The experience is the doorway. Integration is the practice.

Can I drive or work the next day?+

Yes, but most people sleep well that night and prefer a quiet morning. Plan light obligations for the next day.