alcoholFull doseFullEarly signal

Ten people, and drinking that dropped only after dosing began

Ten people, and drinking that did not move until the dosing began.

2015Published
Single-group open-label proof-of-concept trialStudy type
10 peopleSample
What our evidence ratings mean

What they did

Ten adults with alcohol dependence received one or two supervised psilocybin sessions alongside a course of motivational therapy, with drinking tracked for thirty-six weeks.

What they found

Drinking did not change during the four therapy-only weeks before dosing. Heavy drinking days and drinking days both fell significantly after the first psilocybin session and the reduction largely held through week thirty-six.

36 wksof tracking
4 wksof therapy alone with no change

Worth knowing

Ten people with no control group. The four therapy-only weeks are a clever internal comparison but they are not a substitute for randomisation.

Bogenschutz et al. Psilocybin-assisted treatment for alcohol dependence, a proof-of-concept study. Journal of Psychopharmacology, 2015.

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A lot of our customers arrive from the sober curious side rather than the psychedelic side. If that is you, the alcohol research below is the most relevant on the whole shelf. See what we make.

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