Eight people monitored a full day, and no physical hazard
What they did
Eight healthy volunteers received placebo and four ascending psilocybin doses, with twenty-four hour heart tracing, blood pressure, hormone and attention measures taken each time.
What they found
Psychological effects increased with dose while heart rate and body temperature were unchanged. Mean arterial blood pressure rose moderately an hour after the highest dose. The authors reported no indication of physical hazard.
Worth knowing
Eight healthy screened people. Blood pressure is the finding to carry forward if you have a cardiovascular condition, and it is a reason to talk to a doctor rather than a reason to worry.
Hasler et al. Acute psychological and physiological effects of psilocybin in healthy humans. Psychopharmacology, 2004.
Read the sourceKeep reading
adverse eventsNo serious harms in healthy people, some in psychiatric patientsdose responseEffects rose with dose, and most found the experience pleasantharm rankingPsilocybin ranked least harmful of twenty drugs, alcohol mostThe headline finding worth carrying around is that risk concentrates in people with existing psychiatric conditions and in unsupervised settings. If either applies to you, talk to a doctor before you start anything.
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