Mood rose on dosing days, and so did neuroticism
What they did
Ninety-eight people already microdosing gave daily ratings of psychological functioning across six weeks. Sixty-three of them also completed mood, attention and wellbeing batteries at the start and the end.
What they found
Reported functioning rose on dosing days with limited carryover to non-dosing days. Depression and stress fell across the six weeks, but neuroticism went up. A separate group of 263 people expected larger benefits than the study actually measured.
Worth knowing
The expectancy sub-study is the interesting part. People consistently predicted bigger gains than the diaries recorded, which is the same signal the controlled trials keep picking up.
Polito et al. A systematic study of microdosing psychedelics. PLOS ONE, 2019.
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microdosingSelf-blinded microdosers improved, but so did the placebo groupmicrodosingWhen people guessed right, they felt moremicrodosingTwo more controlled trials, two more null resultsThis is the part of the research that maps most closely to what we make. It is also the thinnest evidence base on the shelf, which is why we describe our capsules as a ritual rather than a remedy. See the range.
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