Microdosers improved a little more than controls over a month
What they did
The same team tracked 953 psilocybin microdosers and 180 non-microdosing comparators for about thirty days using repeated mood, mental health and app-based psychomotor tests.
What they found
Microdosers showed small to medium improvements in depression, anxiety, stress and mood relative to controls, consistent across age, gender and mental health status. Psychomotor gains showed up mainly in older adults.
Worth knowing
Naturalistic, not blinded and not placebo-controlled. The comparison group chose not to microdose rather than being randomly assigned, so expectancy is still very much in play.
Rootman et al. Psilocybin microdosers demonstrate greater observed improvements in mood and mental health at one month. Scientific Reports, 2022.
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microdosingSelf-blinded microdosers improved, but so did the placebo groupmicrodosingWhen people guessed right, they felt moremicrodosingTwo more controlled trials, two more null resultsThis is the part of the research that maps most closely to what we make. It is also the thinnest evidence base on the shelf, which is why we describe our capsules as a ritual rather than a remedy. See the range.
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