personalityFull doseFullModerate evidence

Openness rose after psilocybin, and stayed up a year later

Openness rose and was still elevated more than a year later.

2011Published
Pooled analysis of two controlled session studiesStudy type
52 peopleSample
What our evidence ratings mean

What they did

Researchers tracked the five major personality domains before and after high-dose psilocybin sessions in fifty-two healthy volunteers, measuring again one to two months after and around fourteen months after.

What they found

Openness rose by about 2.8 points overall and by 5.7 points in participants who had a complete mystical-type experience. In that subgroup it was still roughly 4.2 points above baseline more than a year later. The other four domains did not change.

14 monthsand openness still elevated
1 of 5personality domains changed

Worth knowing

Personality is generally considered stable in adulthood, which is what makes this notable and also what should make you cautious. The effect concentrated in a subgroup defined after the fact.

MacLean et al. Mystical experiences occasioned by the hallucinogen psilocybin lead to increases in the personality domain of openness. Journal of Psychopharmacology, 2011.

Read the source

The short version is that full doses make you worse at creative tasks while you are on them and slightly better a week later. Anyone selling you focus in a capsule is ahead of the evidence, including anyone selling capsules.

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