When people guessed right, they felt more
What they did
Thirty-four people beginning to microdose took either half a gram of dried mushrooms or a matched placebo under double-blind conditions, while researchers measured subjective effects, creativity, cognition, perception and brain activity by EEG.
What they found
Stronger subjective effects on the active dose appeared only among participants who correctly guessed which condition they were in. There was no improvement in creativity or cognition, and a few measures shifted slightly toward impairment.
Worth knowing
A small sample, and one that measured acute effects rather than the cumulative benefit most microdosing protocols claim. It does not rule out longer-term effects, it just finds none in the short term.
Cavanna et al. Microdosing with psilocybin mushrooms, a double-blind placebo-controlled study. Translational Psychiatry, 2022.
Read the sourceKeep reading
microdosingSelf-blinded microdosers improved, but so did the placebo groupmicrodosingTwo more controlled trials, two more null resultsmicrodosingNearly nine thousand people, and microdosers reported lower anxiety and depressionThis is the part of the research that maps most closely to what we make. It is also the thinnest evidence base on the shelf, which is why we describe our capsules as a ritual rather than a remedy. See the range.
For education, not medical advice. Every write-up links back to the original source.
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